Database : HANSEN Search on : CAMUNDONGOS ENDOGAMICOS BALB C [Subject descriptor] References found : 34 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 19552 Author: Aarestrup, Fernando Monteiro; Sampaio, Elizabeth Pereira; Moraes, Milton Ozorio de; Albuquerque, Edson C. A; Castro, Ana Paula V; Sarno, Euzenir Nunes. Title: Experimental mycobacterium leprae infection in BALB/c Mice: effect of BCG administration on TNF-a production and granuloma development. Source: Int. J. Lepr;68(2):156-166, Jun., 2000. ilus, graf. Abstract: In the present study, the experimental model of Mycobacterium leprae infection in the foot pads of BALB/c mice was used to investigate the effects of BCG administration on tumor necrosis factor-alpha (TNF-alpha) production and granuloma development. It was observed that mice intravenously infected with BCG 7 months after M. leprae inoculation into the foot pads presented a more effective mycobacteria clearance, revealed by a significant reduction of BCG-colony forming units in the spleen and by the reduction of acid-fast bacilli (AFB) in the foot pads. BCG infection at the peak of M. leprae infection also modulated the granulomatous response to M. leprae by converting mononuclear granulomas into an epithelioid-cell granuloma. Furthermore, lower TNF-alpha serum levels were detected in M. leprae-infected mice when compared to mice infected with M. leprae + BCG. An analysis of the TNF-alpha gene expression in the spleen by semiquantitative reverse transcription-polymerase chain reactions (RT-PCR) demonstrated that co-infection with BCG induced an earlier expression of TNF-alpha mRNA than in M. leprae-infected mice. The numbers of TNF-alpha-positive cells and apoptotic cells were also enhanced in epithelioid versus non-epithelioid granulomas. As a whole, the data suggest that co-infection of M. leprae-infected mice with BCG modulates TNF-alpha synthesis which, in turn, leads to induction of protective epithelioid granuloma formation in the foot pads and subsequent mycobacterial clearance. Macrophage differentiation into epithelioid cells, in association with the enhancement of TNF-alpha production at the granuloma site, may represent a triggering signal that induced apoptosis in these cells, leading to mycobacterial elimination. Moreover, the rate of apoptosis in epithelioid granulomas may well be related to the extent of immunopathologically mediated tissue damage. (AU)^ien. Descriptors: Mycobacterium leprae/imunol Camundongos Endogâmicos BALB C/genet Camundongos Endogâmicos BALB C/imunol Vacina BCG/uso terap Fatores de Necrose Tumoral/genet Fatores de Necrose Tumoral/imunol Limits: Animais Camundongos Electronic Medium: http://hansen.bvs.ilsl.br/textoc/revistas/intjlepr/2000/pdf/v68n2/v68n2a06.pdf / en Location: BR191.1

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Id: 18425 Author: Belone, A. F. F; Madeira, S; Rosa, P. S; Opromolla, Diltor Vladimir Araujo Title: Experimental reproduction of the Jorge Lobo's disease in BALB/c mice inoculated with Lacazia loboi obtained from a previously infected mouse ..- Source: s.l; s.n; 2001. ^f191^l194 p. ilus, graf. Abstract: Long-term maintenance of Lacazia loboi in the laboratory has not been reported. We report here the use BALB/c mice to maintain the Lacazia loboi for extended period of time. Eight to ten week-old mice were inoculated intradermally in both hind footpads with a fungal suspension from a macerated footpad obtained from an original mouse previous infected with the fungi and sacrificed 8 months after inoculation. The inoculated animals were sacrificed at different time intervals, footpads were excised, the right one was submitted to histopathological examination and the left one was macerated in sterile saline for fungal count and viability index determination. The inoculated animals presented the histopathological picture identical to the mice previously inoculated with material from human lesion. Granulomatous infiltrates with predominance of macrophages and giant cells were observed. The granulomas evolved progressively as observed in the different times of sacrifice. After 7 months of inoculation, macroscopic lesions were observed, and the number of fungi obtained from macerated footpads was higher than the number of inoculated fungi. The pattern of lesion development was similar to what was observed in animals infected with a fungal suspension obtained from a human lesion. Considering the histopathological findings, the clinical manifestations, and the finding of a higher number of fungi obtained than the inoculated into footpads of each mice, we believe the BALB/c mice strain is as an excellent way to amintain L. loboi in laboratory. Moreover, even after serial passages of the funfi, the granulomatous lesions are reproduced consistently in laboratory conditions. (AU). Descriptors: BLASTOMICOSE/clas BLASTOMICOSE/etiol BLASTOMICOSE/imunol BLASTOMICOSE/microbiol BLASTOMICOSE/patol BLASTOMICOSE/vet CAMUNDONGOS ENDOGÂMICOS BALB C/imunol CAMUNDONGOS ENDOGÂMICOS BALB C/microbiol - DOOENÇA DE JORGE LOBO  DOOENÇA DE JORGE LOBO  LACAZIA LOBOI Limits: ANIMAL Location: BR191.1; 08748/s

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Id: 17563 Author: Zhang, Liangfen; Budiawan, Teky; Matsuoka, Masanori Title: Diversity of potential short tandem repeats in Mycobacterium leprae and application for molecular typing ..- Source: s.l; s.n; Oct. 2005. 9 p. tab. Abstract: A recent advance in molecular typing for tracing the transmission of leprosy is the discovery of short tandem repeats (STRs) in Mycobacterium leprae. To substantiate polymorphic loci from STR as promising candidates for molecular typing tools in leprosy epidemiology, 44 STR loci including 33 microsatellites and 11 minisatellites were investigated among 27 laboratory strains by sequencing PCR products. Not all STRs were necessarily polymorphic. Thirty-two out of the 44 loci were polymorphic. Nine polymorphic loci were suitable for identifying genotypes according to the discriminatory capacity, stability, and reproducibility. All the strains were classified into independent genotypes by the selected nine loci. Three multi-case households were subjected to molecular typing. M. leprae obtained from household cases showed identical copy numbers by TTC triplet alone, but the isolates from one family contact case were divided into different genotypes by adding eight other polymorphic loci. The combination of information from multiple loci allows increasing levels of discrimination and it is likely that the generation and documentation of data will result in the choice of a potential molecular typing tool for leprosy epidemiology. (AU). Descriptors: Técnica de Tipagem Bacteriana/* DNA Bacteriano/AN Pé/MI Marcadores Genéticos/*GE Hanseníase/EP/MI Camundongos Endogâmicos BALB C Camundongos Nus Repetições de Microssatélites/GE Repetições Mini-Satélites/GE Mycobacterium leprae/*CL/*GE Análise de Sequência de DNA Sequências Repetidas em Tandem/*GE Variação (Genética)/* Limits: Research Support, Non-U.S. Gov't Camundongos Humanos Animais Location: BR191.1; 09342/s

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Id: 17555 Author: Welch, Theodosia M; Gelber, Robert H; Murray, Lydia P; Ng, Herman; O'Neill, Sheila M; Levy, Louis Title: Viability of Mycobacterium leprae after multiplication in mice ..- Source: s.l; s.n; Nov. 1980. 4 p. tab. Abstract: To measure the rate at which Mycobacterium leprae are killed in the course of the mouse footpad infection after the maximum of multiplication has been achieved, M. leprae were harvested shortly before and at intervals after multiplication had reached the level of 10(6) organisms per footpad, serially diluted, and inoculated into the footpads of passage mice. Beginning 1 year later, foot-by-foot harvests of M. leprae were performed from passage mice, and the proportion of viable organisms in the passage inocula was calculated by means of a most-probable-number calculation. In addition, the proportion of solidly staining M. leprae was measured in the passage inocula. The proportion of viable M. leprae in the passage inocula was found to decrease with the time after multiplication to 10(6) organisms per footpad of donor mice; the half-time of loss of viable M. leprae was 25 days. The proportion of solidly staining organisms appeared to be directly related to the proportion of viable organisms, as measured by mouse passage, and inversely proportional to the time after multiplication to 10(6) organisms per footpad. (AU). Descriptors: Hanseníase/IM/*MI Camundongos Endogâmicos BALB C Mycobacterium leprae/*GD/IM Limits: ANIMAL CAMUNDONGOS Research Support, U.S. Gov't, P.H.S. Location: BR191.1; 09334/s

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Id: 13735 Author: Ngamying, Maeya; Sawanpanyalert, Pathom; Butraporn, Raywadee; Nikasri, Junjira; Cho, Sang-Nae; Levy, Louis; Brennan, Patrick J Title: Effect of vaccination with refined components of the organism on infection of mice with Mycobacterium leprae ..- Source: s.l; s.n; 2003. 3 p. tab. Abstract: Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton-the mycolyl-arabinogalactan-peptidoglycan complex-devoid of proteins is not protective. (AU). Descriptors: HANSENIASE/prev VACINAS BACTERIANAS/imunol ESQUELETO DA PAREDE CELULAR/imunol CAMUNDONGOS ENDOGÂMICOS BALB C MYCOBACTERIUM BOVIS/imunol MYCOBACTERIUM LEPRAE/imunol VACINACAO Limits: ANIMAL FEMININO CAMUNDONGOS SUPPORT, U.S. GOV'T, P.H.S. Electronic Medium: http://www.ilsl.br Location: BR191.1

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Id: 13451 Author: Young, Douglas B; Khanolkar, Saroj R; Barg, Linda L; Buchanan, Thomas M Title: Generation and characterization of monoclonal antibodies to the phenolic glycolipid of Mycobacterium leprae ..- Source: s.l; s.n; jan. 1984. 6 p. ilus, tab, graf. Abstract: Nine cloned cell lines producing antibodies to the unique phenolic glycolipid of Mycobacterium leprae have been established as a result of fusions with spleens from mice immunized with the glycolipid complexed with methylated bovine serum albumin. One of the antibodies was relatively nonspecific, binding to a related glycolipid from Mycobacterium kansasii, but the remaining antibodies were specific for the M. leprae lipid. Some of the antibodies required the intact (trisaccharide) carbohydrate portion for recognition of the glycolipid antigen, whereas others recognized partially hydrolyzed forms lacking one or two sugar residues. Monoclonal antibodies directed at the terminal saccharide of the glycolipid showed the greatest specificity for M. leprae in enzyme-linked immunoassays. These antibodies brightly labeled whole mycobacteria in indirect immunofluorescence experiments, demonstrating the surface location of M. leprae-specific determinants of the glycolipid antigen. In addition to their use in providing information about the antigenic properties of the phenolic glycolipid, these antibodies have potential applications for elucidating the roles of glycolipid in the pathogenesis of leprosy.(AU). Descriptors: COMPLEXO ANTIGENO-ANTICORPO ELISA IMUNOFLUORESCÊNCIA GLICOLIPIDIOS/anal GLICOLIPIDIOS/imunol MYCOBACTERIUM LEPRAE CAMUNDONGOS ENDOGÂMICOS BALB C FENOIS PLASMOCITOMA/imunol ESPECIFICIDADE DE ESPECIES Limits: ESTUDO COMPARATIVO ANIMAL CAMUNDONGOS SUPPORT, NON-U.S. GOV'T Electronic Medium: http://www.ilsl.br Location: BR191.1; 01417/s

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Id: 13279 Author: Fieldsteel, A. Howard; Levy, Louis Title: Dapsone chemotherapy of Mycobacterium leprae infection of the neonatally thymectomized Lewis rat ..- Source: s.l; s.n; nov. 1976. 6 p. tab. Abstract: In order to learn whether the neonatally thymectomized Lewis rat (NTLR) infected with Mycobacterium leprae could serve as a model for chemotherapeutic studies in a situation resembling that found in human lepromatous leprosy, NTLR inoculated with M. leprae either locally or intravenously 9 to 16 months earlier were treated for from 1.5 to 8.5 months with dapsone (4,4´-diaminodiphenylsulfone, DDS) incorporated in the rat chow in the concentration providing the minimal inhibitory concentration of the drug for M. leprae and in the 100-fold larger concentration. NTLR were killed at intervals; the M. leprae were counted and passed to mice. Treatment with the smaller dosage of dapsone neither killed M. leprae nor reduced the number of organisms in the bacterial populations, whereas treatment with the larger dosage both killed M. leprae and reduced their numbers. The rate at which the organisms were killed (i.e., rendered noninfective for mice) was much the same as that in patients treated with dapsone in comparable dosage. The dead organisms were removed from the rat tissues at a faster rate than encountered in patients. The NTLR may indeed be suitable for chemotherapeutic studies relevant to man. In addition, the more rapid diappearance of dead M. leprae from the rat tissues may facilitate the study of treatment regimens designed to eradicate persisting viable organisms.(AU). Descriptors: ANIMAIS RECEM-NASCIDOS DAPSONA/admin MODELOS ANIMAIS DE DOENCAS HANSENIASE/quimioter HANSENIASE/parasitol CAMUNDONGOS ENDOGÂMICOS BALB C MYCOBACTERIUM LEPRAE RATOS ENDOGÂMICOS LEW RATOS DE CEPAS ENDOGÂMICAS TIMECTOMIA Limits: ANIMAL MASCULINO FEMININO CAMUNDONGOS RATOS SUPPORT, U.S. GOV'T, P.H.S. Electronic Medium: http://www.ilsl.br Location: BR191.1; 00545/s

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Id: 12309 Author: Kang, Tae-Jin; You, Ji-Chang; Chae, Gue-Tae Title: Identification of catalase-like activity from mucobacterium leprae and the relationship between catalase and isonicotinic acid hydrazide (INH) ..- Source: s.l; s.n; 2001. 7 p. ilus, tab, graf. Descriptors: SULFATO DE AMONIO ANTITUBERCULOSOS SEQUENCIA DE BASES BENZIDINAS CATALASE CATALASE PRIMERS DO DNA DNA COMPLEMENTAR ELETROFORESE EM GEL DE AGAR PEROXIDO DE HIDROGENIO ISONIAZIDA HANSENIASE HANSENIASE MACROFAGOS PERITONEAIS CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE - PEROXIDASE  PEROXIDASES  PEROXIDASES  REAÇAO EM CADEIA POR POLIMERASE  DNA POLIMERASE DIRIGIDO POR RNA  CONTAGEM DE CINTILAÇAO  HOMOLOGIA DE SEQUENCIA DO ACIDO NUCLÉICO  ESPECTROFOTOMETRIA Location: BR191.1; 08638/s

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Id: 12297 Author: Spencer, John S; Marques, Maria Angela M; Lima, Monica C. B. S; Junqueira_Kipnis, Ana Paula; Gregory, Bruce C; Truman, Richard W; Brennan, Patrick J Title: Antigenic specificity of the mycobacterium leprae homologue of ESAT-6 ..- Source: s.l; s.n; Feb. 2002. 4 p. tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ESPECIFICIDADE DE ANTICORPOS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS ANTIGENOS DE BACTÉRIAS CLONAGEM MOLECULAR EPITOPOS DE LINFOCITO B EPITOPOS DE LINFOCITO B EPITOPOS DE LINFOCITO T EPITOPOS DE LINFOCITO T HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C DADOS DE SEQUENCIA MOLECULAR Limits: ANIMAL Location: BR191.1; 08667/s

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Id: 12292 Author: Ohara, Naoya; Matsuoka, Masanori; Nomaguchi, Hiroko; Naito, Mariko; Yamada, Takeshi Title: Protective responses against experimental mycobacterium leprae infection in mice induced by recombinant Bacillus Calmette-Guérin over-producing three putative protective antigen candidates ..- Source: s.l; s.n; Feb. 2001. 5 p. ilus, graf. Descriptors: ANTIGENOS DE BACTÉRIAS VACINA BCG VACINA BCG VACINA BCG SEQUENCIA DE BASES PRIMERS DO DNA HANSENIASE HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C CAMUNDONGOS ENDOGAMICOS C57BL MYCOBACTERIUM BOVIS MYCOBACTERIUM BOVIS Limits: ANIMAL Location: BR191.1; 08623/s

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Id: 12288 Author: Adams, Linda B; Scollard, David M; Ray, Nashome A; Cooper, Andrea M; Frank, Anthony A; Orme, Ian M; Krahenbuhl, James L Title: The study of mycobacterium leprae infection in interferon-gamma gene - disrupted mice as a model to explore the immunopathologic spectrum of leprosy ..- Source: s.l; s.n; 2002. 8 p. ilus, graf. Descriptors: LINFOCITOS T CD4-POSITIVOS LINFOCITOS T CD8-POSITIVOS CITOCINAS MODELOS ANIMAIS DE DOENÇAS CITOMETRIA DE FLUXO PELE PELE DELEÇAO DE GENES IMUNOHISTOQUIMICA INTERFERON TIPO II HANSENIASE HANSENIASE HANSENIASE TRANSFORMAÇAO LINFOCITICA MACROFAGOS PERITONEAIS CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C CAMUNDONGOS KNOCKOUT MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE Limits: ANIMAL Location: BR191.1; 08655/s

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Id: 12231 Author: Dhople, Arvind M Title: In vivo activity of epiroprim, a dihydrofolate reductase inhibitor, singly and in combination with dapsone, against mycobacterium leprae ..- Source: s.l; s.n; 2002. 4 p. tab. Descriptors: ADMINISTRAÇAO ORAL TATUS DAPSONA DAPSONA SINERGISMO DE DROGAS ANTAGONISTAS DO ACIDO FOLICO ANTAGONISTAS DO ACIDO FOLICO LEPROSTATICOS LEPROSTATICOS CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE TRIMETOPRIM TRIMETOPRIM TRIMETOPRIM Limits: ANIMAL Location: BR191.1; 08715/s

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Id: 11755 Author: Adams, Linda B; Scollard, David M; Ray, Nashone A; Cooper, Andrea M; Frank, Anthony A; Orne, Ian M; Krahenbuhl, James L Title: The study of Mycobacterium leprae infection in interferon-y gene-disrupted mice as a model to explore the immunopathologic spectrum of leprosy ..- Source: s.l; s.n; 2002. 8 p. ilus, graf. Descriptors: LINFOCITOS T CD4-POSITIVOS LINFOCITOS T CD8-POSITIVOS CITOCINAS MODELOS ANIMAIS DE DOENÇAS CITOMETRIA DE FLUXO PÉ PÉ DELEÇAO DE GENES IMUNOHISTOQUIMICA INTERFERON TIPO II HANSENIASE HANSENIASE HANSENIASE TRANSFORMAÇAO LINFOCITICA MACROFAGOS PERITONEAIS CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C CAMUNDONGOS KNOCKOUT MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE ANIMAL LINFONODOS/IM Limits: ANIMAL Location: BR191.1; 08511/s

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Id: 11686 Author: Ohara, Naoya; Matsuoka, Masanori; Nomaguchi, Hiroko; Naito, Mariko; Yamada, Takeshi Title: Protective responses against experimental Mycobacterium leprae infection in mice induced by recombinant Bacillus Calmette-Guérin over-producing three putative protective antigen candidates ..- Source: s.l; s.n; 2001. 5 p. ilus, graf. Descriptors: MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE MYCOBACTERIUM BOVIS MYCOBACTERIUM BOVIS HANSENIASE HANSENIASE ANTIGENOS DE BACTÉRIAS VACINA BCG VACINA BCG VACINA BCG SEQUENCIA DE BASES PRIMERS DO DNA CAMUNDONGOS ENDOGAMICOS BALB C CAMUNDONGOS ENDOGAMICOS C57BL PLASMIDEOS BAÇO Limits: ANIMAL MASCULINO CAMUNDONGOS Location: BR191.1; 08478/s

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Id: 11651 Author: Nakanga, Kazue; Nomaguchi, Hiroko; Matsuoka, Masanori Title: Establishment of mouse cell lines expressing Micobacterium leprae 65KDa heat shock protein gene ..- Source: s.l; s.n; 1996. 8 p. graf. Descriptors: HANSENIASE MYCOBACTERIUM LEPRAE LINHAGEM CELULAR CHAPERONINAS CHAPERONINAS EXPRESSAO GENICA CAMUNDONGOS ENDOGAMICOS BALB C RNA MENSAGEIRO LINFOCITOS T CITOTOXICOS TRANSFECÇAO Location: BR191.1; 08462/s

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Id: 11322 Author: Naito, Mariko; Matsuoka, Masanori; Ohara, Naoya; Nomaguchi, Hiroko; Yamada, Takeshi Title: The antigen 85 complex vaccine against experimental mycobacterium leprae infection in mice ..- Source: s.l; s.n; 2000. 4 p. tab, graf. Descriptors: ANTIGENOS DE BACTÉRIAS VACINAS BACTERIANAS INTERFERON TIPO II HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MYCOBACTERIUM LEPRAE BAÇO BAÇO CAMUNDONGOS NUS Limits: ANIMAL Location: BR191.1; 07261/s

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Id: 11316 Author: Shimoji, Yoshihiro; Ng, Vincent; Matsumura, Kiichiro; Fischetti, Vincent A; Rambukkana, Anura Title: A 21-kDa surface protein of mycobacterium leprae binds peripheral nerve laminin-2 and mediates Schwann cell invasion ..- Source: s.l; s.n; 1999. 6 p. tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS ADESINAS BACTERIANAS ADESINAS BACTERIANAS SEQUENCIA DE BASES ELETROFORESE EM GEL DE POLIACRILAMIDA LAMININA HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MICROSCOPIA IMUNOELETRONICA DADOS DE SEQUENCIA MOLECULAR PESO MOLECULAR MYCOBACTERIUM LEPRAE SISTEMA NERVOSO PERIFÉRICO SISTEMA NERVOSO PERIFÉRICO CÉLULAS DE SCHWANN PROPRIEDADES DE SUPERFICIE CELULAS CULTIVADAS Limits: ANIMAL Location: BR191.1; 07255/s

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Id: 11298 Author: Randhawa, B; Harris, E. B; Prabhakaran, K Title: Bactericidal action of oral ampicillin/sulbactam against mycobacterium leprae ..- Source: s.l; s.n; 1999. 3 p. graf. Descriptors: ADMINISTRAÇAO ORAL AMPICILINA AMPICILINA ANTIBIOTICOS COMBINADOS ANTIBIOTICOS COMBINADOS MEMBRO POSTERIOR HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MODELOS BIOLOGICOS MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE SULBACTAM SULBACTAM Limits: ANIMAL Location: BR191.1; 07237/s

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Id: 11285 Author: Dhople, A. M; Ibanez, M. A Title: In vivo susceptibility of mycobacterium leprae to ofloxacin either singly or in combination with rifampicin and rifabutin: anti-leprosy activity of ofloxacin and ansamycins in mice ..- Source: s.l; s.n; 1994. 3 p. tab. Descriptors: TATUS SINERGISMO DE DROGAS PÉ LEPROSTATICOS HANSENIASE HANSENIASE FIGADO CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MYCOBACTERIUM LEPRAE OFLOXACINA RIFABUTINA RIFAMPINA Limits: ANIMAL Location: BR191.1; 07224/s

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Id: 11272 Author: Ohara, Naoya; Matsuoka, Masanori; Nomaguchi, Hiroko; Naito, Mariko; Yamada, Takeshi Title: Inhibition of multiplication of mycobacterium leprae in mouse foot pads by recombinant bacillus Calmette-Guerin (BCG) ..- Source: s.l; s.n; 2000. 4 p. graf. Descriptors: ANTIGENOS DE BACTÉRIAS VACINA BCG CONTAGEM DE COLONIA MICROBIANA PÉ IMUNIZAÇAO HANSENIASE HANSENIASE HANSENIASE CAMUNDONGOS CAMUNDONGOS ENDOGAMICOS BALB C MYCOBACTERIUM LEPRAE MYCOBACTERIUM LEPRAE VACINAS SINTÉTICAS CAMUNDONGOS NUS Location: BR191.1; 07452/s

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